Izinto ezibolayo azinawo umthelela omkhulu emvelweni, zihlangabezana nentuthuko esimeme, zingaxazulula ngempumelelo inkinga yemvelo nezinye izinkinga, ngakho-ke isidingo siyakhula, imikhiqizo yokupakisha ebolayo isetshenziswa kabanzi kuzo zonke izindlela zokuphila. Ngenxa yokuthi izinto eziningi ezisetshenziswa ekupakisheni zingokwemvelo futhi zingonakaliswa ngaphandle kokwengeza i-catalyst, lezi zixazululo zisetshenziswa kabanzi embonini yokudla neziphuzo. Izimboni eziningi kanye nohulumeni bathathe izinyathelo zokunciphisa imfucuza yezinto ezibonakalayo kanye nomthelela emvelweni. Izinkampani ezifana ne-Unilever kanye ne-P & G zithembise ukushintshela ezixazululweni zokupakisha zemvelo futhi zinciphise umthelela wazo emvelweni (ikakhulukazi ukukhishwa kwekhabhoni) ngo-50%, okungenye yezinto eziqhuba ukusetshenziswa kokupakisha okubolayo ezimbonini ezahlukahlukene. Izinto ezintsha ezengeziwe, njengezixazululo zokupakisha ezenzakalelayo nezihlakaniphile embonini, ziyanda ziye emikhiqizweni yokugcina.
Abantu abaningi abanomthwalo wemfanelo bathuthela ezixazululweni zokupakisha eziqhubekayo.
Inani labantu emhlabeni selidlule izigidigidi ezingu-7.2, okukhona kuzo abangaphezu kwezigidigidi ezingu-2.5 abaneminyaka ephakathi kuka-15 no-35. Babheka imvelo njengento ebaluleke kakhulu. Ngokuhlanganiswa kwentuthuko yezobuchwepheshe kanye nokukhula kwenani labantu emhlabeni wonke, amapulasitiki nephepha kusetshenziswa kabanzi ezimbonini ezahlukene. Izinto zokupakisha ezitholakala emithonjeni ehlukahlukene (ikakhulukazi amapulasitiki) zakha imfucuza ebalulekile eqinile, eyingozi kakhulu emvelweni. Amazwe amaningi (ikakhulukazi amazwe athuthukile) anemithetho eqinile yokunciphisa imfucuza nokukhuthaza ukusetshenziswa kwezinto zokupakisha ezibolayo.